From the intestinal flora to the microbiome.

Digestivo, Hospital Royo Villanova, España. Atención Primaria, Centro de Salud Fernando El Católico..

Revista espanola de enfermedades digestivas. 2018;(1):51-56
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Abstract

In this article, the history of the microbiota is reviewed and the related concepts of the microbiota, microbiome, metagenome, pathobiont, dysbiosis, holobiont, phylotype and enterotype are defined. The most precise and current knowledge about the microbiota is presented and the metabolic, nutritional and immunomodulatory functions are reviewed. Some gastrointestinal diseases whose pathogenesis is associated with the intestinal microbiota, including inflammatory bowel disease, irritable bowel syndrome and celiac disease, among others, are briefly discussed. Finally, some prominent and promising data with regard to the fecal microbiota transplantation in certain digestive illness are discussed.

Methodological quality

Publication Type : Historical Article ; Review

Metadata

MeSH terms : Gastroenterology ; Intestines